MedCheck in English No.31 Download PDF Free
Contents
Editorial
Why a harmful and useless agent became an expensive new drug?
New Products
Alzheimer’s new drug “donanemab”:
・Increases hemorrhagic stroke with deaths
Web-Appendix Free
・If you want to see Japanese-written documents in which
hemorrhagic stroke events are described, please refer:
Web-Appendix in Japanese Free
・Summary opinion of this review distributed by Kyodo News
(October 30, 2024) and some recent example clippings with
English translation: News paper clippings Free
Adverse Reactions
Paroxetine:
Hostility, aggression, violence, agitation and crime
MedCheck in English No.30 Download PDF Free
Contents
Editorial
What the Government Should Do Before Introducing the Replicon Vacce
(self-amplifying mRNA vaccine)
New Products related
Palivizumab (Synagis®): in RSV high-risk Children
Is it useful for preventing RSV infection?
Supplementary Appendix Free
New Products
Nirsevimab (Beyfortus®): for universal immunization against RSV
RSV-related hospitalizations decrease, but deaths increase
Supplementary Appendix Free
MedCheck No 29 (May 2024) Download Corrected PDF Free
Contents
Editorial
Healthy vaccinee effect: a key bias in observational studies
Review
HPV vaccine increase total and cancer mortality without evidence of HPV-related cancer decrease
1.RCTs show increased cancer and total mortality
2. All observational studies failed to provide evidence for invasive cancer prevention
3. Column: Healthy vaccinee effect in observational studies
Supplementary Appendix Free
Erratum
References 23 and 24 for the main text are corrected to as ffollows:
23) Wheeler CM, Skinner SR, Del Rosario-Raymundo MR, Garland SM, Chatterjee A, Lazcano-Ponce E, et al. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double blind, randomised controlled VIVIANE study. Lancet Infectious Diseases 2016;16(10):1154-68.
24) Skinner SR, Szarewski A, Romanowski B, Garland SM, Lazcano-Ponce E, Salmeron J. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 4-year interim follow-up of the phase 3, double-blind, randomised controlled VIVIANE study. Lancet 2014;384(9961): 2213–27.
MedCheck No 28 (December 2023) Download PDF Free
Contents
Editorial
Unavoidable adverse reactions to Alzheimer’ s agent
Review
Lecanemab removes substitute of lost cells leading to brain
hemorrhage and atrophy
Vaccine Information
Is it true： “Several vaccines reduce Alzheimer’ s disease” ?
Beware of distortion by healthy-vaccine effect
New Products
GLP-1 agonist for obesity: Semaglutide (Wegovy)
Too many adverse effects including suicide. Do not use ！
Errata for line 13-14, left column on p54 (PDF is already corrected)
Before:
Adrenergic-mediated action is essential for weight
loss with GLP-1 agonists [16].
Corrected:
Adrenergic-mediated action is essential for weight
loss with GLP-1 agonists, because GLP-1 did not decrease
body weight of triple beta-adrenoreceptor knockout
mice [16]
MedCheck No 27 (September 2023) Download PDF Free
Contents
Editorial
Be Vigilant On a New Anti-Alzheimer’s Drug
Review
Lecanemab for Alzheimer’s disease
No evidence to delay progress, should not be approved
Supplementary Appendix Free
COVID-19 Information
SARS-CoV-2 Vaccine Increases Arryuthmia Mortality
Supplementary Appendix Free
SARS-CoV-2 Vaccine Increases Venous Thrombosis Mortality
Supplementary Appendix Free
Vaccines and monoclonal antidies: ineffective
Supplementary Appendix Free
