MedCheck No29 (May 2024)New

MedCheck No 29 (May 2024) Download Corrected PDF Free

Contents
Editorial

Healthy vaccinee effect: a key bias in observational studies


Review

HPV vaccine increase total and cancer mortality without evidence of HPV-related cancer decrease

1.RCTs show increased cancer and total mortality
2. All observational studies failed to provide evidence for invasive cancer prevention
3.  Column: Healthy vaccinee effect in observational studies
Supplementary Appendix Free

Erratum
References 23 and 24 of the main text are corrected to as ffollows:
23) Wheeler CM, Skinner SR, Del Rosario-Raymundo MR, Garland SM, Chatterjee A, Lazcano-Ponce E, et al. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double blind, randomised controlled VIVIANE study. Lancet Infectious Diseases 2016;16(10):1154-68.
24) Skinner SR, Szarewski A, Romanowski B, Garland SM, Lazcano-Ponce E, Salmeron J. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 4-year interim follow-up of the phase 3, double-blind, randomised controlled VIVIANE study. Lancet 2014;384(9961): 2213–27.

MedCheck No 28 (December 2023)

MedCheck No 28 (December 2023) Download PDF Free

Contents

Editorial
  Unavoidable adverse reactions to Alzheimer s agent

Review
  Lecanemab removes substitute of lost cells leading to brain
  hemorrhage and atrophy

Vaccine Information
     Is it trueSeveral vaccines reduce Alzheimer s disease ?
       Beware of distortion by healthy-vaccine effect

New Products
    GLP-1 agonist for obesity: Semaglutide (Wegovy)
       Too many adverse effects including suicide. Do not use


Errata for line 13-14, left column on p54 (PDF is already corrected)

Before:
           Adrenergic-mediated action is essential for weight
       loss with GLP-1 agonists [16]. 
Corrected: 
            Adrenergic-mediated action is essential for weight
        loss with GLP-1 agonists, because GLP-1 did not decrease
       body weight of triple beta-adrenoreceptor knockout
        mice [16]

MedCheck No 27 (September 2023)

MedCheck No 27 (September 2023) Download PDF Free

Contents

Editorial
Be Vigilant On a New Anti-Alzheimer’s Drug


Review

Lecanemab for Alzheimer’s disease
 No evidence to delay progress, should not be approved
          Supplementary Appendix Free


COVID-19 Information

SARS-CoV-2 Vaccine Increases Arryuthmia Mortality
          Supplementary Appendix Free

SARS-CoV-2 Vaccine Increases Venous Thrombosis Mortality
          Supplementary Appendix Free

Vaccines and monoclonal antidies: ineffective
          Supplementary Appendix Free

Med Check No 26 (April 2023)

Med Check No 26 (April 2023) Download PDF

Contents

Editorial
Ineffective substances should not be approved

Review
SGLT2 inhibitors should not be used
No proof of efficacy both for diabetes and heart failure

Review
HPV vaccines:
Seriously harmful and do not prevent cervical cancer

Adverse Reactions
Tacrolimus ointment:
Robust carcinogenicity including malignant lymphoma

Med Check – No 25 (December 2022)

Med Check No 25 (December 2022) Download PDF

Contents

Editorial
Unacceptable Proposal: Experts ignored clinical trials
Review
   To be Vaccinated, or Not ? Points You should Know
   SARS-CoV-2 Vaccines Doubles the Risk of COVID-19!
      (1) “Harm-benefit balance” depends on the situation
(2) Types of vaccines and adjuvants
(3) Healthy vaccinee effect (bias)
(4) The doctrine of original antigenic sin and Omicron variants
Figure 6: Types of vaccines and their structures