MedCheck No 29 (May 2024) Download Corrected PDF Free
Contents
Editorial
Healthy vaccinee effect: a key bias in observational studies
Review
HPV vaccine increase total and cancer mortality without evidence of HPV-related cancer decrease
1.RCTs show increased cancer and total mortality
2. All observational studies failed to provide evidence for invasive cancer prevention
3. Column: Healthy vaccinee effect in observational studies
Supplementary Appendix Free
Erratum
References 23 and 24 for the main text are corrected to as ffollows:
23) Wheeler CM, Skinner SR, Del Rosario-Raymundo MR, Garland SM, Chatterjee A, Lazcano-Ponce E, et al. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double blind, randomised controlled VIVIANE study. Lancet Infectious Diseases 2016;16(10):1154-68.
24) Skinner SR, Szarewski A, Romanowski B, Garland SM, Lazcano-Ponce E, Salmeron J. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 4-year interim follow-up of the phase 3, double-blind, randomised controlled VIVIANE study. Lancet 2014;384(9961): 2213–27.
MedCheck No 28 (December 2023) Download PDF Free
Contents
Editorial
Unavoidable adverse reactions to Alzheimer’ s agent
Review
Lecanemab removes substitute of lost cells leading to brain
hemorrhage and atrophy
Vaccine Information
Is it true： “Several vaccines reduce Alzheimer’ s disease” ?
Beware of distortion by healthy-vaccine effect
New Products
GLP-1 agonist for obesity: Semaglutide (Wegovy)
Too many adverse effects including suicide. Do not use ！
Errata for line 13-14, left column on p54 (PDF is already corrected)
Before:
Adrenergic-mediated action is essential for weight
loss with GLP-1 agonists [16].
Corrected:
Adrenergic-mediated action is essential for weight
loss with GLP-1 agonists, because GLP-1 did not decrease
body weight of triple beta-adrenoreceptor knockout
mice [16]
MedCheck No 27 (September 2023) Download PDF Free
Contents
Editorial
Be Vigilant On a New Anti-Alzheimer’s Drug
Review
Lecanemab for Alzheimer’s disease
No evidence to delay progress, should not be approved
Supplementary Appendix Free
COVID-19 Information
SARS-CoV-2 Vaccine Increases Arryuthmia Mortality
Supplementary Appendix Free
SARS-CoV-2 Vaccine Increases Venous Thrombosis Mortality
Supplementary Appendix Free
Vaccines and monoclonal antidies: ineffective
Supplementary Appendix Free
Med Check No 26 (April 2023) Download PDF
Contents
Editorial
Ineffective substances should not be approved
Review
SGLT2 inhibitors should not be used
No proof of efficacy both for diabetes and heart failure
Review
HPV vaccines:
Seriously harmful and do not prevent cervical cancer
Adverse Reactions
Tacrolimus ointment:
Robust carcinogenicity including malignant lymphoma
Med Check No 25 (December 2022) Download PDF
Contents
Editorial
Unacceptable Proposal: Experts ignored clinical trials
Review
To be Vaccinated, or Not ? Points You should Know
SARS-CoV-2 Vaccines Doubles the Risk of COVID-19!
(1) “Harm-benefit balance” depends on the situation
(2) Types of vaccines and adjuvants
(3) Healthy vaccinee effect (bias)
(4) The doctrine of original antigenic sin and Omicron variants
Figure 6: Types of vaccines and their structures
